STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD17RAD17 checkpoint clamp loader component. (680 aa)    
Predicted Functional Partners:
RFC2
Replication factor C subunit 2.
   
 0.997
HUS1
HUS1 checkpoint clamp component.
   
 0.997
RFC3
Replication factor C subunit 3.
   
 0.995
RFC5
Replication factor C subunit 5.
   
0.995
RFC4
Replication factor C subunit 4.
   
 0.995
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 0.988
RAD1
RAD1 checkpoint DNA exonuclease.
   
 0.970
ATRIP
ATR interacting protein.
   
 0.951
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.950
RAD9B
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 0.941
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.