STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)    
Predicted Functional Partners:
PCF11
PCF11 cleavage and polyadenylation factor subunit.
   
 0.990
TSEN15
tRNA splicing endonuclease subunit 15.
    
 
 0.955
TSEN54
tRNA splicing endonuclease subunit 54.
    
 
 0.953
CSTF3
Cleavage stimulation factor subunit 3.
   
 0.933
TSEN34
tRNA splicing endonuclease subunit 34.
   
 0.923
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.915
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 0.871
FIP1L1
Factor interacting with PAPOLA and CPSF1.
    
 0.848
CSTF2
Cleavage stimulation factor subunit 2.
   
 0.844
CSTF2T
RRM domain-containing protein.
   
 0.834
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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