PCSK1 protein (Canis lupus familiaris) - STRING interaction network

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Score

PCSK1

Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)

Predicted Functional Partners:

POMC

0.927

GHRL

0.869

SLC30A8

0.847

MC4R

0.830

BSND

0.803

USP24

0.795

ABCC8

0.758

PAX4

0.740

LDLR

0.692

MC3R

0.677

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	PAX4	ENSCAFP00000060227	ENSCAFP00000002500	ATP binding cassette subfamily C member 8.	Paired box 4.	0.677
ABCC8	PCSK1	ENSCAFP00000060227	ENSCAFP00000011663	ATP binding cassette subfamily C member 8.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.758
ABCC8	SLC30A8	ENSCAFP00000060227	ENSCAFP00000001179	ATP binding cassette subfamily C member 8.	Solute carrier family 30 member 8.	0.817
BSND	LDLR	ENSCAFP00000028021	ENSCAFP00000043416	Barttin CLCNK type accessory beta subunit.	Low density lipoprotein receptor.	0.692
BSND	PCSK1	ENSCAFP00000028021	ENSCAFP00000011663	Barttin CLCNK type accessory beta subunit.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.803
BSND	USP24	ENSCAFP00000028021	ENSCAFP00000028007	Barttin CLCNK type accessory beta subunit.	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.	0.806
GHRL	MC3R	ENSCAFP00000007641	ENSCAFP00000043232	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	Melanocortin-3 receptor.	0.630
GHRL	MC4R	ENSCAFP00000007641	ENSCAFP00000000126	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	Melanocortin-4 receptor.	0.896
GHRL	PAX4	ENSCAFP00000007641	ENSCAFP00000002500	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	Paired box 4.	0.638
GHRL	PCSK1	ENSCAFP00000007641	ENSCAFP00000011663	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.869
GHRL	POMC	ENSCAFP00000007641	ENSCAFP00000006163	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	Proopiomelanocortin.	0.956
LDLR	BSND	ENSCAFP00000043416	ENSCAFP00000028021	Low density lipoprotein receptor.	Barttin CLCNK type accessory beta subunit.	0.692
LDLR	PCSK1	ENSCAFP00000043416	ENSCAFP00000011663	Low density lipoprotein receptor.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.692
LDLR	USP24	ENSCAFP00000043416	ENSCAFP00000028007	Low density lipoprotein receptor.	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.	0.692
MC3R	GHRL	ENSCAFP00000043232	ENSCAFP00000007641	Melanocortin-3 receptor.	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	0.630
MC3R	MC4R	ENSCAFP00000043232	ENSCAFP00000000126	Melanocortin-3 receptor.	Melanocortin-4 receptor.	0.901
MC3R	PCSK1	ENSCAFP00000043232	ENSCAFP00000011663	Melanocortin-3 receptor.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.677
MC3R	POMC	ENSCAFP00000043232	ENSCAFP00000006163	Melanocortin-3 receptor.	Proopiomelanocortin.	0.998
MC4R	GHRL	ENSCAFP00000000126	ENSCAFP00000007641	Melanocortin-4 receptor.	Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.	0.896
MC4R	MC3R	ENSCAFP00000000126	ENSCAFP00000043232	Melanocortin-4 receptor.	Melanocortin-3 receptor.	0.901