STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)    
Predicted Functional Partners:
PTGR1
Prostaglandin reductase 1.
   
 0.964
PTGES
Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
     
 0.955
PTGR2
Uncharacterized protein.
   
 0.949
PTGES2
Prostaglandin E synthase 2.
     
 0.915
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
 
  
 0.912
PRXL2B
Peroxiredoxin like 2B.
     
 0.906
DCXR
Dicarbonyl and L-xylulose reductase.
  
 
  0.846
CBR3
Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.836
LOC610164
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.832
LOC607806
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
0.806
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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