STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2AIPCDKN2A interacting protein. (578 aa)    
Predicted Functional Partners:
TRAPPC11
Trafficking protein particle complex 11.
   
  
 0.707
XRN2
5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.
   
 
 0.705
TMEM145
Transmembrane protein 145.
      
 0.702
TUSC3
Tumor suppressor candidate 3.
   
  
 0.660
PCM1
Pericentriolar material 1.
   
 
 0.653
CDKN2A
Cyclin dependent kinase inhibitor 2B.
    
 
 0.630
ANGPT4
Angiopoietin 4.
      
 0.578
STOX2
Storkhead box 2.
   
  
 0.574
ANGPTL6
Angiopoietin like 6.
      
 0.574
WWC2
WW and C2 domain containing 2.
   
 
 0.550
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.