STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRG3Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa)    
Predicted Functional Partners:
PAPPA
Pappalysin 1.
    
 
 0.760
ACTN3
Actinin alpha 3.
    
 0.560
MYH1
Myosin-1; Muscle contraction.
   
  
 0.542
PAPPA2
Pappalysin 2.
    
 
 0.521
TNN
Tenascin N.
    
  0.509
YPEL4
Protein yippee-like; Belongs to the yippee family.
   
 
 0.484
ZACN
Zinc-activated ligand-gated ion channel; Zinc-activated ligand-gated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
   0.465
RMND5A
Required for meiotic nuclear division 5 homolog A.
    
   0.463
TNR
Tenascin R.
    
  0.460
TNC
Tenascin C.
    
  0.460
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.