PLS1 protein (Canis lupus familiaris) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

PLS1

Plastin 1. (629 aa)

Predicted Functional Partners:

NCKAP1

0.817

AEN

0.811

EXOC1

0.699

UNC93B1

0.663

CAPZB

0.659

AP3M1

0.657

AP1S2

0.647

MED21

0.637

BBC3

0.590

RPAP3

0.575

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEN	BBC3	ENSCAFP00000042661	ENSCAFP00000054385	Apoptosis enhancing nuclease.	Uncharacterized protein.	0.562
AEN	NCKAP1	ENSCAFP00000042661	ENSCAFP00000021253	Apoptosis enhancing nuclease.	NCK associated protein 1.	0.785
AEN	PLS1	ENSCAFP00000042661	ENSCAFP00000011696	Apoptosis enhancing nuclease.	Plastin 1.	0.811
AEN	UNC93B1	ENSCAFP00000042661	ENSCAFP00000045931	Apoptosis enhancing nuclease.	Unc-93 homolog B1, TLR signaling regulator.	0.572
AP1S2	AP3M1	ENSCAFP00000057583	ENSCAFP00000022596	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.571
AP1S2	MED21	ENSCAFP00000057583	ENSCAFP00000052409	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.661
AP1S2	PLS1	ENSCAFP00000057583	ENSCAFP00000011696	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Plastin 1.	0.647
AP3M1	AP1S2	ENSCAFP00000022596	ENSCAFP00000057583	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.571
AP3M1	MED21	ENSCAFP00000022596	ENSCAFP00000052409	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.683
AP3M1	PLS1	ENSCAFP00000022596	ENSCAFP00000011696	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	Plastin 1.	0.657
BBC3	AEN	ENSCAFP00000054385	ENSCAFP00000042661	Uncharacterized protein.	Apoptosis enhancing nuclease.	0.562
BBC3	NCKAP1	ENSCAFP00000054385	ENSCAFP00000021253	Uncharacterized protein.	NCK associated protein 1.	0.508
BBC3	PLS1	ENSCAFP00000054385	ENSCAFP00000011696	Uncharacterized protein.	Plastin 1.	0.590
CAPZB	PLS1	ENSCAFP00000065479	ENSCAFP00000011696	Capping actin protein of muscle Z-line subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Plastin 1.	0.659
EXOC1	PLS1	ENSCAFP00000051070	ENSCAFP00000011696	Exocyst complex component 1.	Plastin 1.	0.699
EXOC1	RPAP3	ENSCAFP00000051070	ENSCAFP00000013568	Exocyst complex component 1.	RNA polymerase II associated protein 3.	0.775
MED21	AP1S2	ENSCAFP00000052409	ENSCAFP00000057583	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.661
MED21	AP3M1	ENSCAFP00000052409	ENSCAFP00000022596	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.683
MED21	PLS1	ENSCAFP00000052409	ENSCAFP00000011696	Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Plastin 1.	0.637
NCKAP1	AEN	ENSCAFP00000021253	ENSCAFP00000042661	NCK associated protein 1.	Apoptosis enhancing nuclease.	0.785