STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPC4APTransient receptor potential cation channel subfamily C member 4 associated protein. (797 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.978
CRBN
Cereblon.
    
 0.923
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
     
 0.920
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.888
DCAF4
DDB1 and CUL4 associated factor 4.
   
 
 0.883
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.870
DCAF6
DDB1 and CUL4 associated factor 6.
    
 0.837
DCAF5
DDB1 and CUL4 associated factor 5.
     
 0.784
DCAF12
DDB1 and CUL4 associated factor 12.
     
 0.782
EDEM2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
 
 
  
 0.776
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.