STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASB14Ankyrin repeat and SOCS box containing 14. (587 aa)    
Predicted Functional Partners:
MTPN
Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity).
  
 
 
 0.575
ASB4
Ankyrin repeat and SOCS box containing 4.
  
  
0.536
SHOC1
Shortage in chiasmata 1.
      
 0.523
ANKRA2
Ankyrin repeat family A member 2.
  
     0.521
ANKRD49
Ankyrin repeat domain 49.
  
     0.505
IQUB
IQ motif and ubiquitin domain containing.
    
 
 0.497
BTD
Biotinidase.
    
 0.487
ANKRD22
Ankyrin repeat domain 22.
  
     0.478
NFKBIB
NFKB inhibitor beta.
  
 
  0.462
HRC
Histidine rich calcium binding protein.
   
 
 0.460
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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