STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASB14Ankyrin repeat and SOCS box containing 14. (587 aa)    
Predicted Functional Partners:
ANKRD9
Ankyrin repeat domain 9.
      
 0.637
HRC
Histidine rich calcium binding protein.
   
 
 0.591
KLHL21
Kelch like family member 21.
    
 
 0.570
MTPN
Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity).
  
 
 
 0.544
ANKRA2
Ankyrin repeat family A member 2.
  
   
 0.522
ANKRD49
Ankyrin repeat domain 49.
  
    0.507
TRIM63
Tripartite motif containing 63.
   
 
 0.495
UBE3C
Ubiquitin protein ligase E3C.
    
 
 0.485
ANKRD22
Ankyrin repeat domain 22.
  
     0.478
SCN4B
Sodium voltage-gated channel beta subunit 4.
      
 0.440
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.