STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)    
Predicted Functional Partners:
STIM1
Stromal interaction molecule 1.
    
 0.993
TRPC5
Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.987
TRPC4
Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.981
TRPV2
Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.934
TRPC3
Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.905
CACNA1H
Calcium voltage-gated channel subunit alpha1 H.
     
 0.905
STIM2
Stromal interaction molecule 2.
    
 
 0.897
TRPC7
Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.896
TRPM4
Transient receptor potential cation channel subfamily M member 4.
    
 
 0.896
CACNA1G
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
     
 0.895
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.