STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWC2WW and C2 domain containing 2. (1175 aa)    
Predicted Functional Partners:
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
   
 
 0.666
LATS1
Large tumor suppressor kinase 1.
    
 
 0.589
TMEM145
Transmembrane protein 145.
   
  
 0.574
TRAPPC11
Trafficking protein particle complex 11.
   
  
 0.572
USP22
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
      
 0.561
CDKN2AIP
CDKN2A interacting protein.
   
 
 0.550
SLC44A5
Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family.
   
  
 0.549
ARHGEF26
Rho guanine nucleotide exchange factor 26.
      
 0.536
CPED1
Cadherin like and PC-esterase domain containing 1.
      
 0.532
SNX17
Sorting nexin 17.
   
  
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.