STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (474 aa)    
Predicted Functional Partners:
SQLE
Squalene epoxidase.
  
 
 0.992
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.988
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
  
 0.984
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.962
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
 0.957
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.947
PDSS1
Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
  
 0.942
PDSS2
Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
  
 0.942
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
  
 
 0.938
FNTA
Farnesyltransferase, CAAX box, alpha.
     
 0.934
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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