STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEIL2Nei like DNA glycosylase 2. (373 aa)    
Predicted Functional Partners:
NEIL1
Nei like DNA glycosylase 1.
   
 
 0.986
OGG1
8-oxoguanine DNA glycosylase.
     
 0.899
POLB
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
   
 
 0.849
XRCC1
Uncharacterized protein.
   
 
 0.835
APLF
Aprataxin and PNKP like factor.
   
  
 0.785
EME1
Essential meiotic structure-specific endonuclease 1.
      
 0.781
SMUG1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
      
 0.751
PNKP
Polynucleotide kinase 3'-phosphatase.
     
 0.748
SUOX
Sulfite oxidase.
   
  
 0.675
UVSSA
UV stimulated scaffold protein A.
      
 0.674
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.