STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)    
Predicted Functional Partners:
DCC
DCC netrin 1 receptor.
    
 0.989
ADIPOR2
Adiponectin receptor 2.
   
 0.987
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 0.986
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.912
PAQR6
Progestin and adipoQ receptor family member 6.
    
 0.905
PAQR5
Progestin and adipoQ receptor family member 5.
    
 0.905
ENSCAFP00000066555
Uncharacterized protein.
    
 0.905
PAQR8
Progestin and adipoQ receptor family member 8.
    
 0.898
PAQR7
Progestin and adipoQ receptor family member 7.
    
 0.898
PAQR9
Progestin and adipoQ receptor family member 9.
    
  0.897
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.