STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BLKTyrosine-protein kinase. (500 aa)    
Predicted Functional Partners:
FGFR4
Fibroblast growth factor receptor.
   
  0.946
FGFR3
Fibroblast growth factor receptor 3.
   
  0.946
PLCG2
Phosphoinositide phospholipase C.
   
0.938
MAK
Male germ cell associated kinase.
   
   0.932
CILK1
Intestinal cell kinase.
   
   0.932
BANK1
B cell scaffold protein with ankyrin repeats 1.
   
 0.928
FGR
Tyrosine-protein kinase.
   
   0.909
CD19
CD19 molecule.
   
 0.907
CD79B
CD79b molecule.
   
 0.862
EGFR
Receptor protein-tyrosine kinase.
    
 0.861
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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