TERF1 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

TERF1

Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (431 aa)

Predicted Functional Partners:

POT1

0.997

TINF2

0.992

ACD

0.988

TERF2IP

0.984

TNKS

0.976

TNKS2

0.964

TERF2

0.952

FBXO4

0.944

TERB1

0.910

ATM

0.876

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD	POT1	ENSCAFP00000032488	ENSCAFP00000002549	ACD shelterin complex subunit and telomerase recruitment factor.	Protection of telomeres 1.	0.993
ACD	TERF1	ENSCAFP00000032488	ENSCAFP00000011804	ACD shelterin complex subunit and telomerase recruitment factor.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.988
ACD	TERF2	ENSCAFP00000032488	ENSCAFP00000050156	ACD shelterin complex subunit and telomerase recruitment factor.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.994
ACD	TERF2IP	ENSCAFP00000032488	ENSCAFP00000029733	ACD shelterin complex subunit and telomerase recruitment factor.	TERF2 interacting protein.	0.994
ACD	TINF2	ENSCAFP00000032488	ENSCAFP00000035708	ACD shelterin complex subunit and telomerase recruitment factor.	TERF1 interacting nuclear factor 2.	0.997
ACD	TNKS	ENSCAFP00000032488	ENSCAFP00000009960	ACD shelterin complex subunit and telomerase recruitment factor.	Poly [ADP-ribose] polymerase.	0.410
ATM	POT1	ENSCAFP00000035996	ENSCAFP00000002549	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Protection of telomeres 1.	0.459
ATM	TERF1	ENSCAFP00000035996	ENSCAFP00000011804	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.876
ATM	TERF2	ENSCAFP00000035996	ENSCAFP00000050156	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.778
ATM	TINF2	ENSCAFP00000035996	ENSCAFP00000035708	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	TERF1 interacting nuclear factor 2.	0.533
FBXO4	TERF1	ENSCAFP00000027426	ENSCAFP00000011804	F-box protein 4.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.944
POT1	ACD	ENSCAFP00000002549	ENSCAFP00000032488	Protection of telomeres 1.	ACD shelterin complex subunit and telomerase recruitment factor.	0.993
POT1	ATM	ENSCAFP00000002549	ENSCAFP00000035996	Protection of telomeres 1.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.459
POT1	TERB1	ENSCAFP00000002549	ENSCAFP00000030265	Protection of telomeres 1.	Telomere repeat binding bouquet formation protein 1.	0.407
POT1	TERF1	ENSCAFP00000002549	ENSCAFP00000011804	Protection of telomeres 1.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.997
POT1	TERF2	ENSCAFP00000002549	ENSCAFP00000050156	Protection of telomeres 1.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.990
POT1	TERF2IP	ENSCAFP00000002549	ENSCAFP00000029733	Protection of telomeres 1.	TERF2 interacting protein.	0.997
POT1	TINF2	ENSCAFP00000002549	ENSCAFP00000035708	Protection of telomeres 1.	TERF1 interacting nuclear factor 2.	0.995
POT1	TNKS	ENSCAFP00000002549	ENSCAFP00000009960	Protection of telomeres 1.	Poly [ADP-ribose] polymerase.	0.464
TERB1	POT1	ENSCAFP00000030265	ENSCAFP00000002549	Telomere repeat binding bouquet formation protein 1.	Protection of telomeres 1.	0.407