STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF366Zinc finger protein 366. (691 aa)    
Predicted Functional Partners:
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.825
OTX2
Orthodenticle homeobox 2.
   
 
 0.655
HHEX
Hematopoietically expressed homeobox.
   
 0.617
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
      
 0.609
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
 
 0.606
PPWD1
Peptidylprolyl isomerase domain and WD repeat containing 1.
    
 
 0.600
CTBP2
C-terminal binding protein 2.
    
 0.587
TMEM171
Transmembrane protein 171.
    
 
 0.549
MST1
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 
 0.544
ZFP36
ZFP36 ring finger protein.
   
 
 0.530
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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