Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
U2SURPU2 snRNP associated SURP domain containing. (1029 aa)    
Predicted Functional Partners:
CHERP
Calcium homeostasis endoplasmic reticulum protein.
   
 0.998
RBM17
RNA binding motif protein 17.
   
 0.994
SF3A2
Splicing factor 3a subunit 2.
    
 0.986
DDX46
DEAD-box helicase 46.
   
 0.967
SF3B1
Splicing factor 3b subunit 1.
   
 0.960
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
 0.957
PRPF40A
Pre-mRNA processing factor 40 homolog A.
   
 
 0.942
SMNDC1
Survival motor neuron domain containing 1.
   
 0.923
SF3A1
Splicing factor 3a subunit 1.
   
0.921
SF3B3
Splicing factor 3b subunit 3.
   
 0.921
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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