STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HESX1HESX homeobox 1. (186 aa)    
Predicted Functional Partners:
LHX3
LIM homeobox 3.
   
 
 0.787
POU1F1
Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
   
 
 0.613
TMEM126A
Transmembrane protein 126A.
      
 0.584
NAV2
Neuron navigator 2.
   
 
 0.568
PKNOX2
PBX/knotted 1 homeobox 2.
   
 
 0.560
FOXB2
Forkhead box B2.
   
  
 0.551
SIX6
SIX homeobox 6.
   
 
 0.536
ZNF146
Zinc finger protein 146.
   
 
 0.528
GTF3C2
General transcription factor IIIC subunit 2.
   
 
 0.523
HHEX
Hematopoietically expressed homeobox.
   
  
 0.506
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.