STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (270 aa)    
Predicted Functional Partners:
ENSCAFP00000054759
Ubiquitin-like domain-containing protein.
   
 0.979
RPS18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family.
   
 0.976
RPS28
Ribosomal protein S28.
   
 0.975
RPS7
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
   
 0.973
RPS12
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
   
 0.972
RPS15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
   
 0.961
RPS13
Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
  
 0.957
RPS25
40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.
   
 0.956
RPS29
Uncharacterized protein.
   
 0.955
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]
   
 0.953
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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