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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR66WD repeat domain 66. (1267 aa)    
Predicted Functional Partners:
SYCE2
Synaptonemal complex central element protein 2.
   
 
 0.539
MEIOB
Meiosis specific with OB-fold.
    
 
 0.534
CFAP54
Cilia and flagella associated protein 54.
    
 
 0.533
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
 
      0.531
TEX12
Testis expressed 12.
      
 0.526
WDR54
WD repeat domain 54.
      
 0.515
SPATA22
Spermatogenesis associated 22.
      
 0.515
CFAP44
Cilia and flagella associated protein 44.
   
 
0.506
KDM4D
Lysine demethylase 4D.
    
 
 0.499
BTG4
BTG anti-proliferation factor 4.
   
  
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.