STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL17RDInterleukin 17 receptor D. (594 aa)    
Predicted Functional Partners:
IL17RC
Interleukin 17 receptor C.
    
 0.889
IL17RE
Interleukin 17 receptor E.
    
 0.874
IL25
Interleukin 25.
    
 0.818
IL17C
Interleukin 17C.
    
 0.769
IL17F
Interleukin 17F.
    
 0.722
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
      
 0.695
IL17A
Interleukin 17A.
    
 0.651
CSK
Tyrosine-protein kinase.
    
 0.636
SRC
Tyrosine-protein kinase.
    
 0.636
ARHGEF3
Rho guanine nucleotide exchange factor 3.
 
 
  
 0.620
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.