STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRSS48Serine protease 48; Belongs to the peptidase S1 family. (311 aa)    
Predicted Functional Partners:
GLYATL3
Glycine-N-acyltransferase like 3.
   
  
 0.530
ENSCAFP00000058636
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
     0.530
SCAF11
SR-related CTD associated factor 11.
    
 
 0.527
DDI1
DNA damage inducible 1 homolog 1.
      
 0.525
ENSCAFP00000047054
Peptidase S1 domain-containing protein.
  
     0.474
TRIM68
Tripartite motif containing 68.
    
 
 0.454
CA10
Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family.
    
 
 0.410
SH3D19
SH3 domain containing 19.
      
 0.403
EXOSC4
Exosome component 4.
      
 0.401
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
      
 0.401
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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