STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEAD1TEA domain transcription factor 1. (498 aa)    
Predicted Functional Partners:
YAP1
Yes associated protein 1.
   
 0.969
WWTR1
WW domain containing transcription regulator 1.
   
 0.945
TCF7L2
Transcription factor 7 like 2.
   
 0.809
TCF7
Transcription factor 7.
    
 0.797
TCF7L1
Transcription factor 7 like 1.
    
 0.786
LEF1
Lymphoid enhancer binding factor 1.
    
 0.752
LATS1
Large tumor suppressor kinase 1.
   
 
 0.714
TEAD4
Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
     
  0.711
INSM2
INSM transcriptional repressor 2.
    
 
 0.699
VGLL4
Vestigial like family member 4.
    
 
 0.699
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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