STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM70Transmembrane protein 70. (308 aa)    
Predicted Functional Partners:
ECSIT
ECSIT signalling integrator.
    
 
 0.947
NDUFS5
NADH:ubiquinone oxidoreductase subunit S5.
   
 
 0.942
ZCCHC17-2
Uncharacterized protein.
      
 0.810
ZCCHC17
CCHC-type domain-containing protein.
      
 0.810
ACSS1
Acetyl-coenzyme A synthetase.
    
   0.771
MRPL49
Mitochondrial ribosomal protein L49.
   
  
 0.757
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2.
   
  
 0.735
MTERF4
Uncharacterized protein.
      
 0.715
THEM4
Thioesterase superfamily member 4.
      
 0.713
POPDC2
Popeye domain containing 2.
      
 0.701
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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