STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1965 aa)    
Predicted Functional Partners:
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.949
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.949
CXXC1
CXXC finger protein 1.
   
 
 0.915
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
   
 
 0.908
WDR5
WD repeat domain 5.
   
 0.855
LOC612517
zf-CpG_bind_C domain-containing protein.
   
 
 0.838
KMT2C
Lysine methyltransferase 2C.
   
0.729
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
0.729
KMT2B
Lysine methyltransferase 2B.
   
0.729
KMT2D
Lysine methyltransferase 2D.
   
0.729
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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