GDAP1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GDAP1

Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)

Predicted Functional Partners:

HOXA1

0.830

CRISPLD1

0.830

UNC5C

0.826

PLTP

0.800

MFN2

0.798

GHITM

0.722

GIPC2

0.627

CLDN14

0.616

CDC42EP2

0.609

AEBP2

0.595

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEBP2	CDC42EP2	ENSCAFP00000018329	ENSCAFP00000020121	AE binding protein 2.	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	0.688
AEBP2	CLDN14	ENSCAFP00000018329	ENSCAFP00000014226	AE binding protein 2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.468
AEBP2	GDAP1	ENSCAFP00000018329	ENSCAFP00000012037	AE binding protein 2.	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	0.595
AEBP2	GIPC2	ENSCAFP00000018329	ENSCAFP00000036530	AE binding protein 2.	GIPC PDZ domain containing family member 2.	0.605
AEBP2	HOXA1	ENSCAFP00000018329	ENSCAFP00000004350	AE binding protein 2.	Homeobox A1.	0.692
CDC42EP2	AEBP2	ENSCAFP00000020121	ENSCAFP00000018329	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	AE binding protein 2.	0.688
CDC42EP2	CLDN14	ENSCAFP00000020121	ENSCAFP00000014226	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.452
CDC42EP2	GDAP1	ENSCAFP00000020121	ENSCAFP00000012037	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	0.609
CDC42EP2	GIPC2	ENSCAFP00000020121	ENSCAFP00000036530	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	GIPC PDZ domain containing family member 2.	0.612
CDC42EP2	HOXA1	ENSCAFP00000020121	ENSCAFP00000004350	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	Homeobox A1.	0.687
CLDN14	AEBP2	ENSCAFP00000014226	ENSCAFP00000018329	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	AE binding protein 2.	0.468
CLDN14	CDC42EP2	ENSCAFP00000014226	ENSCAFP00000020121	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	0.452
CLDN14	GDAP1	ENSCAFP00000014226	ENSCAFP00000012037	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	0.616
CLDN14	GIPC2	ENSCAFP00000014226	ENSCAFP00000036530	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	GIPC PDZ domain containing family member 2.	0.538
CLDN14	HOXA1	ENSCAFP00000014226	ENSCAFP00000004350	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Homeobox A1.	0.700
CRISPLD1	GDAP1	ENSCAFP00000012147	ENSCAFP00000012037	Cysteine rich secretory protein LCCL domain containing 1.	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	0.830
GDAP1	AEBP2	ENSCAFP00000012037	ENSCAFP00000018329	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	AE binding protein 2.	0.595
GDAP1	CDC42EP2	ENSCAFP00000012037	ENSCAFP00000020121	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.	0.609
GDAP1	CLDN14	ENSCAFP00000012037	ENSCAFP00000014226	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.616
GDAP1	CRISPLD1	ENSCAFP00000012037	ENSCAFP00000012147	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.	Cysteine rich secretory protein LCCL domain containing 1.	0.830