STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRTM1Leucine rich repeats and transmembrane domains 1. (345 aa)    
Predicted Functional Partners:
CORIN
Corin, serine peptidase.
    
 
 0.674
LMX1A
LIM homeobox transcription factor 1 alpha.
    
 
 0.614
CNTN2
Contactin 2.
    
 
 0.602
LRR1
Leucine rich repeat protein 1.
  
   
 0.486
CLSTN2
Calsyntenin 2.
      
 0.477
CCL3
C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family.
    
 
 0.462
LRRC8B
Leucine rich repeat containing 8 VRAC subunit B.
  
   
 0.445
CA10
Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.439
SRSF5
Serine and arginine rich splicing factor 5.
   
 
 0.429
E2RBZ7_CANLF
Uncharacterized protein.
    
  0.426
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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