STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORAI1ORAI calcium release-activated calcium modulator 1. (300 aa)    
Predicted Functional Partners:
STIM1
Stromal interaction molecule 1.
   
 
 0.994
STIM2
Stromal interaction molecule 2.
   
 
 0.929
ESYT3
Extended synaptotagmin 3.
   
  
 0.717
GPRIN2
G protein regulated inducer of neurite outgrowth 2.
   
  
 0.693
ESYT2
Extended synaptotagmin 2.
      
 0.681
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.664
TRPC3
Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.618
SARAF
Store-operated calcium entry associated regulatory factor.
   
 
 0.586
CRACR2A
Calcium release activated channel regulator 2A.
    
 
 0.584
KCNH1
Potassium voltage-gated channel subfamily H member 1.
   
  
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.