STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMBOX1Homeobox containing 1. (438 aa)    
Predicted Functional Partners:
FAM160B2
Family with sequence similarity 160 member B2.
      
 0.829
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
      
 0.610
TMEM109
Transmembrane protein 132A.
      
 0.595
MEIOB
Meiosis specific with OB-fold.
      
 0.556
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
      
 0.549
NAT10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
      
 0.545
PRKCQ
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
      
 0.528
RBM17
RNA binding motif protein 17.
      
 0.519
PAQR9
Progestin and adipoQ receptor family member 9.
      
 0.511
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
      
 0.476
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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