STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMBOX1Homeobox containing 1. (438 aa)    
Predicted Functional Partners:
FAM160B2
Family with sequence similarity 160 member B2.
   
  
 0.858
TMEM109
Transmembrane protein 132A.
      
 0.646
ZBTB48
Zinc finger and BTB domain containing 48.
   
 
 0.607
ZNF827
Zinc finger protein 827.
   
 
 0.606
RBM17
RNA binding motif protein 17.
   
  
 0.564
PAQR9
Progestin and adipoQ receptor family member 9.
      
 0.561
HIPK1
Homeodomain interacting protein kinase 1.
   
 
 0.545
NR2C2
Nuclear receptor subfamily 2 group C member 2.
   
  
 0.493
TIMM17A
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
      
 0.485
NTRK3
Tyrosine-protein kinase receptor.
   
  
 0.458
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.