STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZFHX4Zinc finger homeobox 4. (3623 aa)    
Predicted Functional Partners:
CHD4
Chromodomain helicase DNA binding protein 4.
    
 
 0.793
XIRP2
Xin actin binding repeat containing 2.
      
 0.628
NFIB
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.593
SKIDA1
SKI/DACH domain containing 1.
      
 0.591
ZFAND2A
Chromosome 6 C7orf50 homolog.
      
 0.591
LCP2
Lymphocyte cytosolic protein 2.
      
 0.587
PRR16
Proline rich 16.
      
 0.575
NDRG1
N-myc downstream regulated 1.
      
 0.565
ATXN7
Ataxin 7.
      
 0.563
CSMD3
CUB and Sushi multiple domains 3.
      
 0.559
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.