STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQP6Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)    
Predicted Functional Partners:
AQP11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
   
  
 0.836
AQP3
Uncharacterized protein.
  
   
0.729
RHBG
Ammonium transporter Rh type B; Functions as a specific ammonium transporter.
   
 
 0.720
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
   
 
 0.692
FBXW9
F-box and WD repeat domain containing 9.
   
 
 0.672
ANKRD23
Ankyrin repeat domain 39.
    
 
 0.639
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
   
 
 0.617
BSND
Barttin CLCNK type accessory beta subunit.
   
  
 0.617
MTF2
Metal response element binding transcription factor 2.
      
 0.610
RPL3L
Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family.
    
 
 0.598
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.