P2RX4 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

P2RX4

P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)

Predicted Functional Partners:

P2RX2

0.647

P2RX3

0.643

P2RY1

0.637

P2RX7

0.628

P2RX1

0.596

P2RX5

0.580

P2RX6

0.512

PANX1

0.463

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
P2RX1	P2RX2	ENSCAFP00000028598	ENSCAFP00000009417	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.677
P2RX1	P2RX3	ENSCAFP00000028598	ENSCAFP00000066381	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.700
P2RX1	P2RX4	ENSCAFP00000028598	ENSCAFP00000012316	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.596
P2RX1	P2RX5	ENSCAFP00000028598	ENSCAFP00000039858	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.606
P2RX1	P2RX6	ENSCAFP00000028598	ENSCAFP00000042799	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.656
P2RX1	P2RX7	ENSCAFP00000028598	ENSCAFP00000012359	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.683
P2RX1	P2RY1	ENSCAFP00000028598	ENSCAFP00000039988	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Purinergic receptor P2Y1 variant 1; Belongs to the G-protein coupled receptor 1 family.	0.515
P2RX2	P2RX1	ENSCAFP00000009417	ENSCAFP00000028598	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.677
P2RX2	P2RX3	ENSCAFP00000009417	ENSCAFP00000066381	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.763
P2RX2	P2RX4	ENSCAFP00000009417	ENSCAFP00000012316	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.647
P2RX2	P2RX5	ENSCAFP00000009417	ENSCAFP00000039858	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.627
P2RX2	P2RX6	ENSCAFP00000009417	ENSCAFP00000042799	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.503
P2RX2	P2RX7	ENSCAFP00000009417	ENSCAFP00000012359	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.706
P2RX3	P2RX1	ENSCAFP00000066381	ENSCAFP00000028598	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.700
P2RX3	P2RX2	ENSCAFP00000066381	ENSCAFP00000009417	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.763
P2RX3	P2RX4	ENSCAFP00000066381	ENSCAFP00000012316	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.643
P2RX3	P2RX5	ENSCAFP00000066381	ENSCAFP00000039858	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.620
P2RX3	P2RX6	ENSCAFP00000066381	ENSCAFP00000042799	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.458
P2RX3	P2RX7	ENSCAFP00000066381	ENSCAFP00000012359	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.660
P2RX4	P2RX1	ENSCAFP00000012316	ENSCAFP00000028598	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.596