STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC38A7Solute carrier family 38 member 7. (463 aa)    
Predicted Functional Partners:
COPS7A
COP9 signalosome subunit 7A.
      
 0.881
PNPO
Pyridoxamine 5'-phosphate oxidase.
      
 0.826
CARHSP1
Calcium regulated heat stable protein 1.
   
  
 0.767
SLC38A9
Solute carrier family 38 member 9.
      
0.637
SLC66A1
Solute carrier family 66 member 1.
   
  
 0.618
EIF5B
Eukaryotic translation initiation factor 5B.
      
 0.554
SLC43A2
Solute carrier family 43 member 2.
      
 0.554
LAMTOR1
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.
    
 
 0.553
SLC7A4
Solute carrier family 7 member 4.
   
 
 0.528
LOC479795
Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
      
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.