STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCDIN3DBCDIN3 domain containing RNA methyltransferase. (353 aa)    
Predicted Functional Partners:
PRMT3
Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
      
 0.705
SETD7
SET domain containing 7, histone lysine methyltransferase.
    
 
 0.683
J9P631_CANLF
mRNA cap 0 methyltransferase domain-containing protein.
      
 0.654
ENSCAFP00000050690
mRNA cap guanine-N7 methyltransferase.
      
 0.654
WDR4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
      
 0.640
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 
 0.626
SETD2
SET domain containing 2, histone lysine methyltransferase.
    
 
 0.566
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
   
 
 0.526
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
      
 0.526
METTL21A
Methyltransferase like 21A.
      
 0.516
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.