STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BCDIN3DBCDIN3 domain containing RNA methyltransferase. (353 aa)    
Predicted Functional Partners:
METTL15
Methyltransferase like 15.
      
 0.827
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
    
 
 0.670
SART3
Spliceosome associated factor 3, U4/U6 recycling protein.
    
 
 0.667
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 
 0.662
BCL7B
BAF chromatin remodeling complex subunit BCL7B.
      
 0.598
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.591
BUD23
BUD23 rRNA methyltransferase and ribosome maturation factor.
      
 0.591
LSM6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
   0.568
METTL21A
Methyltransferase like 21A.
      
 0.563
J9P631_CANLF
mRNA cap 0 methyltransferase domain-containing protein.
      
 0.547
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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