STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGAAspartylglucosaminidase. (343 aa)    
Predicted Functional Partners:
NEU4
Sialidase domain-containing protein.
   
 0.724
FUT1
L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.
      
 0.625
ALOX5
Arachidonate 5-lipoxygenase.
   
  
 0.609
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
      
 0.598
FH
Fumarate hydratase.
     
  0.530
OTC
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
     
 0.513
ASNS
Asparagine synthetase [glutamine-hydrolyzing].
     
 0.511
ASNSD1
Glutamine amidotransferase type-2 domain-containing protein.
     
 0.511
GALC
Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (By similarity); Belongs to the glycosyl hydrolase 59 family.
      
 0.487
IDS
Iduronate 2-sulfatase.
      
 0.486
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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