STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCKAP5LNCK associated protein 5 like. (1292 aa)    
Predicted Functional Partners:
CERS5
Ceramide synthase 5.
      
 0.872
DIP2B
Disco interacting protein 2 homolog B.
      
 0.856
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
      
 0.813
ARID2
AT-rich interaction domain 2.
      
 0.641
SCN8A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.568
TMEM59L
Transmembrane protein 59 like.
      
 0.515
TEX2
Testis expressed 2.
      
 0.491
MOB3B
MOB kinase activator 3B.
      
 0.482
RAB11FIP4
RAB11 family interacting protein 4.
      
 0.482
WDFY2
WD repeat and FYVE domain containing 2.
      
 0.457
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]