STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCP10L2Tcp10_C domain-containing protein. (616 aa)    
Predicted Functional Partners:
SASS6
SAS-6 centriolar assembly protein.
   
 
 0.860
STIL
STIL centriolar assembly protein.
    
 0.814
ITSN2
Intersectin 2.
   
 
 0.796
TUBG1
Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
    
 
 0.780
PLK4
Polo like kinase 4.
   
 
 0.756
PDE4DIP
Phosphodiesterase 4D interacting protein.
    
 
 0.746
PCNT
Pericentrin.
   
 
 0.668
AKAP9
A-kinase anchoring protein 9.
   
 
 0.668
CEP135
Centrosomal protein 135.
   
 
 0.662
TBC1D31
TBC1 domain family member 31.
   
 
 0.661
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.