STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)    
Predicted Functional Partners:
P2RX2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.911
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
  
0.902
P2RX3
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
  
  
0.893
P2RX6
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
  
 
0.887
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.844
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.839
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
     
 0.824
CHRNA7
Uncharacterized protein.
     
 0.801
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
     
  0.795
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
     
 0.791
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.