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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC486100FAD-binding PCMH-type domain-containing protein. (440 aa)    
Predicted Functional Partners:
RGN
Regucalcin.
  
 
 0.974
SYCN
Syncollin.
   
  
 0.754
NR1I2
Nuclear receptor subfamily 1 group I member 2.
   
 
 0.730
GBA
Glucosylceramidase.
    
 
 0.720
INPP5D
Inositol polyphosphate-5-phosphatase D.
      
 0.705
PNLIP
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.639
CCR5
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
      
 0.616
NGEF
Neuronal guanine nucleotide exchange factor.
      
 0.611
KLRB1
Killer cell lectin like receptor B1.
      
 0.611
ALG12
Mannosyltransferase.
   
  
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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