PCGF1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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[Homology]

Score

PCGF1

Polycomb group ring finger 1. (259 aa)

Predicted Functional Partners:

RING1

0.997

PCGF5

0.994

BMI1

0.991

PCGF3

0.991

CBX8

0.990

PCGF6

0.986

RNF2

0.982

PCGF2

0.982

KDM2B

0.977

CBX2

0.975

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMI1	CBX2	ENSCAFP00000050138	ENSCAFP00000037305	RING-type domain-containing protein.	Chromobox 2.	0.986
BMI1	CBX8	ENSCAFP00000050138	ENSCAFP00000047965	RING-type domain-containing protein.	Chromobox 8.	0.986
BMI1	KDM2B	ENSCAFP00000050138	ENSCAFP00000060509	RING-type domain-containing protein.	Lysine demethylase 2B.	0.777
BMI1	PCGF1	ENSCAFP00000050138	ENSCAFP00000012421	RING-type domain-containing protein.	Polycomb group ring finger 1.	0.991
BMI1	PCGF2	ENSCAFP00000050138	ENSCAFP00000024338	RING-type domain-containing protein.	Polycomb group ring finger 2.	0.996
BMI1	PCGF3	ENSCAFP00000050138	ENSCAFP00000050579	RING-type domain-containing protein.	Polycomb group ring finger 3.	0.981
BMI1	PCGF5	ENSCAFP00000050138	ENSCAFP00000010769	RING-type domain-containing protein.	Polycomb group ring finger 5.	0.986
BMI1	PCGF6	ENSCAFP00000050138	ENSCAFP00000038996	RING-type domain-containing protein.	Polycomb group ring finger 6.	0.987
BMI1	RING1	ENSCAFP00000050138	ENSCAFP00000001328	RING-type domain-containing protein.	E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...]	0.990
BMI1	RNF2	ENSCAFP00000050138	ENSCAFP00000019876	RING-type domain-containing protein.	Ring finger protein 2.	0.983
CBX2	BMI1	ENSCAFP00000037305	ENSCAFP00000050138	Chromobox 2.	RING-type domain-containing protein.	0.986
CBX2	CBX8	ENSCAFP00000037305	ENSCAFP00000047965	Chromobox 2.	Chromobox 8.	0.996
CBX2	KDM2B	ENSCAFP00000037305	ENSCAFP00000060509	Chromobox 2.	Lysine demethylase 2B.	0.691
CBX2	PCGF1	ENSCAFP00000037305	ENSCAFP00000012421	Chromobox 2.	Polycomb group ring finger 1.	0.975
CBX2	PCGF2	ENSCAFP00000037305	ENSCAFP00000024338	Chromobox 2.	Polycomb group ring finger 2.	0.997
CBX2	PCGF3	ENSCAFP00000037305	ENSCAFP00000050579	Chromobox 2.	Polycomb group ring finger 3.	0.944
CBX2	PCGF5	ENSCAFP00000037305	ENSCAFP00000010769	Chromobox 2.	Polycomb group ring finger 5.	0.961
CBX2	PCGF6	ENSCAFP00000037305	ENSCAFP00000038996	Chromobox 2.	Polycomb group ring finger 6.	0.951
CBX2	RING1	ENSCAFP00000037305	ENSCAFP00000001328	Chromobox 2.	E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...]	0.995
CBX2	RNF2	ENSCAFP00000037305	ENSCAFP00000019876	Chromobox 2.	Ring finger protein 2.	0.982