STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD6SET domain containing 6, protein lysine methyltransferase. (574 aa)    
Predicted Functional Partners:
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.959
NFKBID
NFKB inhibitor delta.
    
 
 0.812
NOB1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
    0.800
NFKB2
Nuclear factor kappa B subunit 2.
    
  0.753
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
      
 0.649
REL
REL proto-oncogene, NF-kB subunit.
    
 
 0.632
RELB
RELB proto-oncogene, NF-kB subunit.
    
 
 0.632
RAD21
RAD21 cohesin complex component.
      
 0.593
POLR3C
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.556
SETD4
SET domain containing 4.
    
 
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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