STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDIL3EGF like repeats and discoidin domains 3. (480 aa)    
Predicted Functional Partners:
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
 
 
    0.732
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 
 0.727
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
 
 
    0.632
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
 
 
    0.568
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 
 0.463
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 
 0.463
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 
 0.463
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.441
AASDH
Aminoadipate-semialdehyde dehydrogenase.
     
 0.439
ATP7B
ATPase copper transporting beta.
  
 
 0.435
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.