STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC113Coiled-coil domain containing 113. (431 aa)    
Predicted Functional Partners:
CFAP100
Cilia and flagella associated protein 100.
    
 
 0.937
WDR78
WD repeat domain 78.
   
 
 0.911
CCDC39
Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.
   
 
 0.876
CCDC151
Coiled-coil domain containing 151.
   
 
 0.875
DRC7
Dynein regulatory complex subunit 7.
  
 
 0.871
CCDC42
Coiled-coil domain containing 42.
  
 
 0.870
CCDC114
Coiled-coil domain containing 114.
   
 
 0.853
CCDC96
Coiled-coil domain containing 96.
   
 
 0.850
DNALI1
Dynein axonemal light intermediate chain 1.
  
 
 0.849
CCDC63
Coiled-coil domain containing 63.
   
 
 0.848
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.