DLGAP4 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DLGAP4

DLG associated protein 4. (991 aa)

Predicted Functional Partners:

DLG4

0.912

SHANK2

0.822

ECSCR

0.784

TENT2

0.777

RILPL1

0.777

CCNB3

0.776

DLG3

0.767

KAT6A

0.761

DLG2

0.732

DLGAP2

0.717

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNB3	DLGAP4	ENSCAFP00000062608	ENSCAFP00000012515	G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).	DLG associated protein 4.	0.776
CCNB3	ECSCR	ENSCAFP00000062608	ENSCAFP00000041381	G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).	Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2 (By similarity).	0.779
CCNB3	KAT6A	ENSCAFP00000062608	ENSCAFP00000008454	G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.775
CCNB3	RILPL1	ENSCAFP00000062608	ENSCAFP00000048273	G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).	Rab interacting lysosomal protein like 1.	0.778
CCNB3	SHANK2	ENSCAFP00000062608	ENSCAFP00000015375	G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).	SH3 and multiple ankyrin repeat domains 2.	0.586
DLG2	DLG3	ENSCAFP00000046898	ENSCAFP00000053258	Discs large MAGUK scaffold protein 2.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.902
DLG2	DLG4	ENSCAFP00000046898	ENSCAFP00000061210	Discs large MAGUK scaffold protein 2.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.953
DLG2	DLGAP2	ENSCAFP00000046898	ENSCAFP00000054188	Discs large MAGUK scaffold protein 2.	DLG associated protein 2.	0.678
DLG2	DLGAP4	ENSCAFP00000046898	ENSCAFP00000012515	Discs large MAGUK scaffold protein 2.	DLG associated protein 4.	0.732
DLG2	SHANK2	ENSCAFP00000046898	ENSCAFP00000015375	Discs large MAGUK scaffold protein 2.	SH3 and multiple ankyrin repeat domains 2.	0.787
DLG3	DLG2	ENSCAFP00000053258	ENSCAFP00000046898	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 2.	0.902
DLG3	DLG4	ENSCAFP00000053258	ENSCAFP00000061210	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.990
DLG3	DLGAP2	ENSCAFP00000053258	ENSCAFP00000054188	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	DLG associated protein 2.	0.783
DLG3	DLGAP4	ENSCAFP00000053258	ENSCAFP00000012515	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	DLG associated protein 4.	0.767
DLG3	SHANK2	ENSCAFP00000053258	ENSCAFP00000015375	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2.	0.816
DLG4	DLG2	ENSCAFP00000061210	ENSCAFP00000046898	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 2.	0.953
DLG4	DLG3	ENSCAFP00000061210	ENSCAFP00000053258	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.990
DLG4	DLGAP2	ENSCAFP00000061210	ENSCAFP00000054188	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	DLG associated protein 2.	0.849
DLG4	DLGAP4	ENSCAFP00000061210	ENSCAFP00000012515	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	DLG associated protein 4.	0.912
DLG4	SHANK2	ENSCAFP00000061210	ENSCAFP00000015375	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 2.	0.902