VCAN protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

VCAN

Versican. (3401 aa)

Predicted Functional Partners:

DCN

0.836

BCAN

0.759

BGN

0.715

CD44

0.693

SDC1

0.629

CIB4

0.604

SDC4

0.604

TNR

0.587

LUM

0.579

GPC1

0.577

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCAN	DCN	ENSCAFP00000024595	ENSCAFP00000009230	Uncharacterized protein.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.673
BCAN	GPC1	ENSCAFP00000024595	ENSCAFP00000018637	Uncharacterized protein.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.630
BCAN	SDC1	ENSCAFP00000024595	ENSCAFP00000059447	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.624
BCAN	SDC4	ENSCAFP00000024595	ENSCAFP00000058875	Uncharacterized protein.	Syndecan 4.	0.609
BCAN	TNR	ENSCAFP00000024595	ENSCAFP00000036108	Uncharacterized protein.	Tenascin R.	0.849
BCAN	VCAN	ENSCAFP00000024595	ENSCAFP00000012600	Uncharacterized protein.	Versican.	0.759
BGN	DCN	ENSCAFP00000028297	ENSCAFP00000009230	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.450
BGN	LUM	ENSCAFP00000028297	ENSCAFP00000009219	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Lumican.	0.524
BGN	VCAN	ENSCAFP00000028297	ENSCAFP00000012600	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Versican.	0.715
CD44	GPC1	ENSCAFP00000050335	ENSCAFP00000018637	CD44 antigen.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.516
CD44	SDC1	ENSCAFP00000050335	ENSCAFP00000059447	CD44 antigen.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.623
CD44	VCAN	ENSCAFP00000050335	ENSCAFP00000012600	CD44 antigen.	Versican.	0.693
CIB4	VCAN	ENSCAFP00000006660	ENSCAFP00000012600	Calcium and integrin binding family member 4.	Versican.	0.604
DCN	BCAN	ENSCAFP00000009230	ENSCAFP00000024595	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Uncharacterized protein.	0.673
DCN	BGN	ENSCAFP00000009230	ENSCAFP00000028297	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.450
DCN	GPC1	ENSCAFP00000009230	ENSCAFP00000018637	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.609
DCN	LUM	ENSCAFP00000009230	ENSCAFP00000009219	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Lumican.	0.961
DCN	SDC1	ENSCAFP00000009230	ENSCAFP00000059447	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.726
DCN	SDC4	ENSCAFP00000009230	ENSCAFP00000058875	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Syndecan 4.	0.651
DCN	VCAN	ENSCAFP00000009230	ENSCAFP00000012600	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Versican.	0.836