CTSO protein (Canis lupus familiaris) - STRING interaction network

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Score

CTSO

Cathepsin O; Belongs to the peptidase C1 family. (315 aa)

Predicted Functional Partners:

BCL2L1

0.887

XIAP

0.885

BCL2

0.881

CTSZ

0.844

CTSB

0.843

CTSH

0.825

RBM46

0.812

CAMK1

0.810

CTSA

0.808

CTSE

0.797

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BCL2L1	ENSCAFP00000000102	ENSCAFP00000010478	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	BCL2 like 1.	0.995
BCL2	CTSB	ENSCAFP00000000102	ENSCAFP00000059573	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	Cathepsin B; Belongs to the peptidase C1 family.	0.924
BCL2	CTSH	ENSCAFP00000000102	ENSCAFP00000031547	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	Cathepsin H; Belongs to the peptidase C1 family.	0.883
BCL2	CTSO	ENSCAFP00000000102	ENSCAFP00000012615	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	Cathepsin O; Belongs to the peptidase C1 family.	0.881
BCL2	CTSZ	ENSCAFP00000000102	ENSCAFP00000047997	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	Cathepsin Z; Belongs to the peptidase C1 family.	0.887
BCL2	XIAP	ENSCAFP00000000102	ENSCAFP00000034255	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	Baculoviral IAP-repeat containing protein 4.	0.828
BCL2L1	BCL2	ENSCAFP00000010478	ENSCAFP00000000102	BCL2 like 1.	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	0.995
BCL2L1	CTSB	ENSCAFP00000010478	ENSCAFP00000059573	BCL2 like 1.	Cathepsin B; Belongs to the peptidase C1 family.	0.907
BCL2L1	CTSH	ENSCAFP00000010478	ENSCAFP00000031547	BCL2 like 1.	Cathepsin H; Belongs to the peptidase C1 family.	0.883
BCL2L1	CTSO	ENSCAFP00000010478	ENSCAFP00000012615	BCL2 like 1.	Cathepsin O; Belongs to the peptidase C1 family.	0.887
BCL2L1	CTSZ	ENSCAFP00000010478	ENSCAFP00000047997	BCL2 like 1.	Cathepsin Z; Belongs to the peptidase C1 family.	0.907
BCL2L1	XIAP	ENSCAFP00000010478	ENSCAFP00000034255	BCL2 like 1.	Baculoviral IAP-repeat containing protein 4.	0.806
CAMK1	CTSO	ENSCAFP00000007955	ENSCAFP00000012615	Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily.	Cathepsin O; Belongs to the peptidase C1 family.	0.810
CTSA	CTSB	ENSCAFP00000014432	ENSCAFP00000059573	Carboxypeptidase; Belongs to the peptidase S10 family.	Cathepsin B; Belongs to the peptidase C1 family.	0.949
CTSA	CTSE	ENSCAFP00000014432	ENSCAFP00000014987	Carboxypeptidase; Belongs to the peptidase S10 family.	Cathepsin E; Belongs to the peptidase A1 family.	0.764
CTSA	CTSH	ENSCAFP00000014432	ENSCAFP00000031547	Carboxypeptidase; Belongs to the peptidase S10 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.885
CTSA	CTSO	ENSCAFP00000014432	ENSCAFP00000012615	Carboxypeptidase; Belongs to the peptidase S10 family.	Cathepsin O; Belongs to the peptidase C1 family.	0.808
CTSA	CTSZ	ENSCAFP00000014432	ENSCAFP00000047997	Carboxypeptidase; Belongs to the peptidase S10 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.915
CTSB	BCL2	ENSCAFP00000059573	ENSCAFP00000000102	Cathepsin B; Belongs to the peptidase C1 family.	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).	0.924
CTSB	BCL2L1	ENSCAFP00000059573	ENSCAFP00000010478	Cathepsin B; Belongs to the peptidase C1 family.	BCL2 like 1.	0.907