STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)    
Predicted Functional Partners:
CD63
Tetraspanin.
   
 
 0.941
ABI3BP
ABI family member 3 binding protein.
   
  
 0.716
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
      
 0.712
APOB
Apolipoprotein B.
    
 0.703
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
   
  
 0.686
DAB2
DAB adaptor protein 2.
   
 
 0.677
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
   
 
 0.664
TFRC
Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...]
   
 
 0.614
CD81
Tetraspanin.
   
  
 0.588
VAMP8
Vesicle associated membrane protein 8.
   
 
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.