STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F5E2F transcription factor 5. (184 aa)    
Predicted Functional Partners:
TFDP1
Transcription factor.
   
 0.981
TFDP2
Transcription factor Dp-2.
   
 0.975
RBL2
RB transcriptional corepressor like 2.
   
 0.975
RB1
RB transcriptional corepressor 1.
   
 0.968
SMAD3
Mothers against decapentaplegic homolog.
    
 0.945
E2F4
E2F transcription factor 4.
  
 
0.943
SMAD4
Mothers against decapentaplegic homolog.
   
 0.935
SMAD2
Mothers against decapentaplegic homolog.
    
 0.927
RBL1
RB transcriptional corepressor like 1.
   
 
 0.838
E2F3
E2F transcription factor 3.
    
 
0.633
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.