STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F5E2F transcription factor 5. (184 aa)    
Predicted Functional Partners:
TFDP2
Transcription factor Dp-2.
   
 0.997
RBL2
RB transcriptional corepressor like 2.
   
 0.990
TFDP1
Transcription factor.
   
 0.990
RBL1
RB transcriptional corepressor like 1.
   
 0.989
RB1
RB transcriptional corepressor 1.
   
 0.983
E2F4
E2F transcription factor 4.
  
0.982
SMAD4
Mothers against decapentaplegic homolog.
    
 0.964
SMAD3
Mothers against decapentaplegic homolog.
    
 0.952
SMAD2
Mothers against decapentaplegic homolog.
    
 0.952
LIN9
Lin-9 DREAM MuvB core complex component.
    
 0.887
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.