STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLL2Metalloendopeptidase. (1021 aa)    
Predicted Functional Partners:
PCOLCE
Procollagen C-endopeptidase enhancer.
   
0.918
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.672
OMA1
OMA1 zinc metallopeptidase.
      
 0.659
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
   
  
 0.655
ARHGAP22
Rho GTPase activating protein 22.
      
 0.637
TTC14
Tetratricopeptide repeat domain 14.
      
 0.636
MME
Uncharacterized protein.
   
  
 0.614
KEL
Kell metallo-endopeptidase.
      
 0.603
TAL2
TAL bHLH transcription factor 2.
   
  
 0.525
MBTPS2
Membrane bound transcription factor peptidase, site 2.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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